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Crohn disease

What is Crohn disease?
Crohn disease is a chronic inflammatory intestinal disease. Its exacerbations alternate with symptomless periods (in some cases, symptoms are still present, but their manifestations are weak). The disease may develop in one or several segments of the intestine, typically beginning from the ileum or bowel.

How prevalent is Crohn disease?
Crohn disease affects 30-50 subjects per 100000 population.

What are the causes of Crohn disease?
The causes of Crohn disease are not known for certain. Scientists attribute its development to certain species of bacteria and viruses, food allergy, environmental factors, smoking, hereditary predisposition, immune disorders, and psychological factors.

How is Crohn disease manifested?
The following symptoms are typical of Crohn disease:
  • acute abdominal pain, especially postprandial, which are often the only manifestation for many years;
  • frequent diarrhea (in 70-80% of cases);
  • blood in feces (occasionally);
  • anal lesions.

  • The extraintestinal manifestations of Crohn disease may include:
  • anemia;
  • fever;
  • оfatigue;
  • weight loss;
  • arthritis;
  • nodal erythema;
  • secondary amenorrhea;
  • aphthous stomatitis;
  • eye lesions.

  • What studies are required to confirm Crohn disease?
    The diagnosis of Crohn disease is confirmed by endoscopic and X-ray examinations, histology, echography, and laboratory diagnostics.

    What are prognoses for Crohn disease patients?
    When the diagnosis of Crohn disease is early enough and the adequate treatment is provided in time, the prognosis is favorable. The prognosis has become still better after novel drugs had been introduces in clinical practice. However, detection of the disease at the advanced stages may require surgery. Therefore, one of the main tasks in dealing with Crohn disease is to diagnose and treat it in time.

    If you experience abdominal pain or other symptoms mentioned above, do not delay your visit to physician. Remember that time is precious! Address gastroenterologists at LenMedCenter where experienced specialists will make the exact diagnosis and choose the right treatment.

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